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KENODOL® 10 mg Tablet: Each box contains 2 x 10 Tablets in Alu-Alu pack. KENODOL® 30 mg Injection: Each box contains 1 Ampoule of 1 ml in Alu-Pvc pack. KENODOL® 60 mg Injection: Each box contains 1 Ampoule of 2 ml in Alu-Pvc pack.

Composition

KENODOL® (Ketorolac Tromethamine) is indicated for the short-term management of moderate to moderately severe acute pain, including post-surgical pain (such as general, orthopaedic and dental surgery), acute musculoskeletal trauma pain and post-partum uterine cramping pain.

Indication

Dosage should be adjusted according to the severity of the pain and the response of the patient. Injection: When administering Ketorolac injection, the IV bolus must be given over no less than 15 seconds. The IM administration should be given slowly and deeply into the muscle. The analgesic effect begins in ~30 minutes with maximum effect in 1 to 2 hours after dosing IV or IM. Duration of analgesic effect is usually 4 to 6 hours. Single dose administration: IV dosing - patients &lt; 65 years of age: 30 mg/day and patients &gt; 65 years of age, renally impaired and/or less than 50 kg of body weight: 15 mg/day. IM dosing - patients &lt; 65 years of age: 60 mg/day and patients &gt; 65 years of age, renally impaired and/or less than 50 kg of body weight: 30 mg/day. Multiple dose administration: Patients &lt; 65 years of age: 30 mg every 6 hours. The maximum daily dose should not exceed 120 mg and patients &gt; 65 years of age, renally impaired and/or less than 50 kg of body weight: 15 mg every 6 hours. The maximum daily dose should not exceed 60 mg. Tablet: The usual oral dose of Ketorolac Tromethamine is 10 mg every 4 to 6 hours as required. Doses exceeding 40 mg per day are not recommended. For patients receiving Ketorolac injections, and who are converted to Ketorolac oral tablets, the total combined daily dose should not exceed 90 mg ( 60 mg for the elderly, renally-impaired patients and patients less than 50 kg) and the oral component should not exceed 40 mg on the day the change of formulation is made. Patients should be converted to oral treatment as soon as possible.

Dosage & Administration

Medications that help alleviate pain and reduce inflammation in the body.

Analgesic & Anti-inflammatory

ORAFEN® SR Tablet: Each sustained release tablet contains Diclofenac Sodium BP 100 mg

ORAFEN®SR is indicated in the following conditions. Tablet: Inflammatory and degenerative froms of Rheumatism: Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout. Acute musculoskeletal disorders: Periarthritise (e.g: frozen sholder), tendinitis, tenosynovitis, bursitis. Pain and Inflammation: Acute musculoskeletal disorders and back pain, Post-traumatic and postoperative pain, inflammation, and swelling, e.g. following dental or orthopaedic surgery, Painful inflammatory conditions in gynaecology and primary dysmenorrhea, fever and pain associated with inflammatory infections of the upper respiratory tract.

Tablet: The recommended daily dose is one tablet preferable at meal time, for rare patient where 100mg/day is unsatisfactory, the dose may be increased to 100 mg b.i.d. if the benefits outweigh the clinical risks of increased side effects.

Ranoxen® 250 Tablets: Each tablet contains Naproxen USP 250 mg. Ranoxen® 500 Tablets: Each tablet contains Naproxen USP 500 mg.

Ranoxen® is indicated for the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and juvenile rheumatoid arthritis. Ranoxen® is also indicated for the treatment of tendonitis, bursitis, acute gout, for the management of pain, primary dysmenorrheal, migraine treatment and prophylaxis.

Onset or pain relief can begin within 1 hour in patients taking Naproxen. A lower dose should be considered in patients with renal or hepatic impairments or in elderly patients. Adults Rheumatoid arthritis, osteoarthritis and ankylosing spondylitis: The recommended dose of Naproxen is 250 mg or 500 mg taken twice daily (morning and evening) or single daily dose of 500-1000mg given morning or evening, or 500 mg taken twice daily or a single daily dose of 1000 mg given in the evening. During long- time administration the dose of naproxen may be adjusted up or down depending on the clinical response of the patient. Acute gout: The recommended starting dose is of 750 mg, followed by 250 mg every 8 hours until the attack has subsided. Dysennorhoea: 500mg should be given initially, followed by 250 mg at 6 to 8 hours intervals for up to 5 days. Analgesia and acute muscular skeletal disorders: 500 mg should be given initially, followed by 250 mg at 6 to 8 hours intervals. Children over 5 years Juvenile rheumatoid arthritis: 10 mg/ kg/ day given as 2 divided doses at 12 hours intervals.

RanoxenTM Plus 500 Tablet: Each tablet contains Naproxen Sodium USP equivalent to Naproxen 500 mg and Esomeprazole Magnesium Trihydrate USP equivalent to Esomeprazole 20 mg.

It is indicated for the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, dysmenorrhea and to decrease the risk of developing gastric ulcers in patients at risk of developing NSAIDs associated gastric ulcers.

Carefully consider the potential benefits and risks of RanoxenTM Plus (Naproxen and Esomeprazole) and other treatment options before deciding to use RanoxenTM Plus (Naproxen and Esomeprazole). Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals. If a dose of Esomeprazole lower than a total daily dose of 40 mg is more appropriate, a different treatment should be considered. For Rheumatoid Arthritis, Osteoarthritis and Ankylosing Spondylitis: The dosage is one tablet twice daily of 375 mg Naproxen and 20 mg of Esomeprazole or 500 mg Naproxen and 20 mg of Esomeprazole.* Do not split, chew, crush or dissolve the tablet. RanoxenTM Plus (Naproxen and Esomeprazole) is to be taken at least 30 minutes before meals. Geriatric Patients: Studies indicate that although total plasma concentration of Naproxen is unchanged, the unbound plasma fraction of Naproxen is increased in the elderly. Use caution when high doses are required and some adjustment of dosage may be required in elderly patients. As with other drugs used in the elderly use the lowest effective dose. Patients with Moderate to Severe Renal Impairment: Naproxen containing products are not recommended for use in patients with moderate to severe or severe renal impairment (creatinine clearance&lt;30 mL/min). Hepatic Insufficiency: Monitor patients with mild to moderate hepatic impairment closely and consider a possible dose reduction based on the Naproxen component of RanoxenTM Plus (Naproxen and Esomeprazole). RanoxenTM Plus (Naproxen and Esomeprazole) is not recommended in patients with severe hepatic impairment because Naproxen may increase the risk of renal failure or bleeding and Esomeprazole doses should not exceed 20 mg daily in these patients.

Each film coated tablet contains Paracetamol BP 500 mg &amp; Caffeine BP 65 mg.

It is recommended for the treatment of fever and most painful and febrile conditions, for example headache including migraine, backache, toothache, neuralgia, rheumatic pain and dysmenorrhea, and relief of the symptoms of cold, influenza and sore throat.

Adults: 1-2 tablets every 4-6 hours. Maximum Dose: 8 tablets daily. Not recommended for children below 12 years.

Pain and inflammation relief aims to alleviate discomfort and swelling caused by injuries, arthritis, infections, or chronic conditions. It involves using medications or natural remedies to reduce pain and promote healing.

Pain and Inflammation Relief

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